91 patients with clinical symptoms of COPD and control group of 24 patients with other diseases have been surveyed during 2008-2010.
The persons of both sexes and of different age categories (from 20 till 70, 58 years old on average) were studied.
In the majority of patients the main clinical symptoms were chronic cough, production of phlegm, a short wind at load. Duration of disease varied from 5 till 15 years.
In 13 patients disease symptoms were manifested gradually, in 69 clinical symptoms developed within last 5 years, and in 6 – in 15 years after beginning of the disease. However in certain cases (n = 3) we observed periods of quick progressing of illness after recovery from viral respiratory infection or prolonged pneumonia. In 45 patients disease symptoms began with the intense intoxication (weakness, sweatiness, lowgrade fever) and cough with phlegm that lasted from 2 weeks (n = 33) to 1 month (n = 24). The most typical and constant clinical sign was the short wind with decreasing of tolerance to physical stress which was marked in patients of advanced age (34%), and it was at rest in 2.7% of patients. In 30 patients with gradual development of disease the short wind was the earliest clinical symptom, aroused at considerable, and then at moderate physical activities.
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