Careful Biophilia tracker-diagnostics of a muscular trauma

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As our researches have shown, in most cases (94.5% of all studied group) bruises and ruptures of muscles are accompanied by hematomas of various forms and sizes. Only in 3 cases at microbruises of muscles sized 5-7 mm no hematomas were revealed. Intermuscular hematomas are located along muscular fibers, at Biophilia tracker-ultramicroscanning they were visualized as hyperchromogenic formations of various forms depending on location in a muscle, changing the form during physical activity. Also, it is obligatory to evaluate the integrity of investigated muscle’s own fascia for diagnostics of possible prolapse of muscular fascicles into fascia prolapse with development of a muscular hernia.
Careful Biophilia tracker-diagnostics of a muscular trauma allows to decide about possibility of its minimum invasive therapy. In sports medicine avoidance of additional operational injuries at trauma treatment is extremely important.

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According to Biophilia tracker results the following groups of traumas are revealed:
1. Muscle microbruises (less than 5 mm) – 36 (65.4%), which in 33 (91.7%) cases were accompanied by development of hematomas sized 1-3 cm longitudinally;
2. Muscle bursting (5-20 mm) – 15 (27.3%), in all cases they were accompanied by hematomas sized 3-5 cm;
3. Ruptures of muscles in 4 (7.3%) patients, among them in 1 (1.8%) we detected complete rupture and in 3 (5.5%) – partial rupture, with formation of hematomas sized 5 cm and more.

Thus, the majority of traumas (94.5%) was represented by bruises of muscles sized less than 20 mm, diagnostics of which by other methods is difficult. At the same time wrong medical tactics and incorrect choice of a training mode at such traumas can lead to development of further damages of a muscle, resulting in restriction of sports activities. This fact specifies the importance of Biophilia tracker-research in diagnostics of a muscular trauma in sportsmen.

The newest Biophilia tracker-research

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According to our data, neurofibromas are located mainly on a border of derma and the upper part subcutaneous fat, and also between subcutaneous fat and muscles, in certain cases – intramuscularly. They can be asymptomatic, be defined by palpation, can be painless or manifested clinically in the form of pain in any segment of a body. At Biophilia tracker-research – neurofibroma is a space-occupying solid neoplasm of high chromogeneity, of homogeneous structure mainly, various size, oval or roundish (less often) shape.

You can not miss a device-Biophilia tracker

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It is known that distinctive signs of the tumors growing from nerve trunks, are their mobility, displaceability to sides and absence of displacement along a nerve trunk. Our research has also shown absence of neoplasms cohesion with surrounding tissues in patients, tumors were mobile enough, especially those located hypodermically. According to references, all benign tumours are characterised by slow growth that corresponds to data gathered during our research, in which duration of tumors growth was 2 – 6 years.
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Why we need the newest Biophilia NLS

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Visual examination of the patient’s left scapular region in a projection of a trapezoid muscle has detected a small swelling. Palpation of left shoulder girdle detected in soft tissues painful space-occupying process of firm-elastic consistence, not connected to surrounding tissues and partially displaced in a frontback direction. Vascular pattern on a skin in the neoplasm area is not changed, skin temperature is normal. There is a distinct pulsation in peripheral vessels of upper extremities. No sensitive and motion abnormalities in fingers of left upper extremity were revealed.
Applied Biophilia NLS-research of left shoulder girdle tissues and left half of neck allowed to make a conclusion that the Biophilia NLS-graphic picture corresponds to NF.

The latest of Biophilis NLS

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Scientific references have descriptions of 8 types of NF, however majority of them, except NF2, are considered to be an abortive form of NF1 and are not considered as independent nosological forms. Exceptions are segmentary NF (NF of 5th type) (NF5) at which typical displays of NF1 are located in one or several neighboring dermatomes (registered extremely seldom, usually it is not inherited), and not included into number 8 spinal NF at which all spinal roots are affected symmetrically (several observations are described).
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Daily Biophilia NLS-monitoring was performed

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One of the important components of acute pancreatitis severity estimation level for definition of treatment methods is the estimation of pathological process spread. In accordance with Savelieva V.S. spread classification (1989) the destructive pancreatitis is divided into limited and widespread.
As can be seen from the above, limited acute pancreatitis demands conservative and/or puncture-drainage treatment under the control of visualizing research methods; draining, and in some cases also suction operative interventions are necessary in case of extended pancreatitis. Within the limits of performed research the limited destructive pancreatitis (haemorrhagic, fatty and purulo-necrotic) was diagnosed in 31 (32,3 %) of cases, spread pancreatitis was diagnosed in 65 (67,7 %) of cases. In case of limited destructive pancreatitis the waiting surgical approach under daily Biophilia NLS-monitoring was performed, at progressing of destructive process (quantity and expansion increase of necrosis zones, presence of suppurative complication) 11 (35,5 %) patients were draining operated. In case of extended pancreatitis regular Biophilia NLS-monitoring of patients in 53 (81,5 %) of cases has shown the progression activity of pathological process which in 36 (67,9 %) of cases required draining operative measures, and in 17 (32,1 %) of cases it required stage sanitation of abdominal cavity and retroperitoneal space.

Biophilia NLS-method takes significant importance in diagnostics of pyoinflammatory diseases

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According to a number of authors this classification has many disadvantages and various readings. In given research we have divided acute pancreatitis for edematic and destructive for greater effectiveness of material analysis. Destructive pancreatitis according to Savelev V.S. classification (1989) has the following forms: haemorrhagic, fatty and purulo-necrotic. Purulo-necrotic complications is the principal lethality cause in case of destructive pancreatitis. Lethality rate at purulo-necrotic complications of acute pancreatitis is 85 %. At present time Biophilia NLS-method takes significant importance in diagnostics of pyoinflammatory diseases of pancreatic gland which allows estimating condition of pancreatic gland in dynamics. Identification of acute pancreatitis form is extremely important because correct information on patient’s condition gives the chance to try to interrupt a pathological chain of disease development by application of the most effective treatment methods at the given form of disease of the patient.

Biophilia NLS diagnosis Acute pancreatitis

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In 1992 at International symposium concerning acute pancreatitis in Atlanta (USA) the classification based on differentiation of intrabelly and system complications of acute pancreatitis taking into account of development features of inflammatory and destructive processes, and also disease severity levels has been recommended for clinical use as a result of agreement of 40 leading surgeons-pancreatologists from 15 countries of the world.
Acute pancreatitis was defined as an acute inflammatory process in pancreatic gland with variable involving of other regional tissues or distant systems and organs.

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A complex of Biophilia tracker-signs of inflammatory changes

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During statistical processing of a material it was found that between a complex of Biophilia tracker-signs of inflammatory changes in an intestinal wall and endoscopic stages of inflammatory process, a strong correlation linl exists, and it is authentic.
Thus, Biophilia tracker-research with use NLS-angiography and Biophilia tracker-ultramicroscanning can be applied both for diagnostics of inflammatory process location in small and large intestine, and for evaluation of inflammatory process activity at observation of patients with Crohn’s disease, along with endoscopic and radiological methods.

Unlike endoscopic and radiological methods of diagnostics, Biophilia tracker-research can be applied without limitations, as it is safe for the patient. For acquiring of high quality information, Biophilia tracker-research of intestines should be done before endoscopy or in 2–3 days after endoscopic research.

Biophilia NLS-graphy data and results of endoscopic researches

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The following data was obtained by comparison of Biophilia NLS-graphy data and results of endoscopic researches.
 At endoscopic remission the structure of an intestinal wall was not changed in 93.3% of cases, affection of vessels was not detected (in 73.3% of patients) or was minor (in 26.7% of patients).

In 1 patient with remission of inflammatory process and pseudopolyposis we revealed ulcerous defects in the form of single hyperchromogenic inclusions in submucous layer, at the same time vessels affections were not expressed. It means that Biophilia NLS-signs should be used only altogether for definition of an inflammatory process stage. Biophilia NLS-research of this patient was carried out on next day after colonoscopy, and gas between pseudo-polyps in segmented intestine was taken for achromogenic cavities in a mucous layer. This case also says that Biophilia NLS-research should be applied before colonoscopy or in 2–3 days after it.

Biophilia NLS-research results analysis

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At the second stage of work we have studied possibilities of Biophilia NLS-research in revealing of destructive changes in small and large intestine at Crohn’s disease. We took endoscopic research for “the gold standard”. Stages of endoscopic changes at this pathology (remission and aggravation stages (aphthoid ulcer, ulcers, ulcers-cracks, scarring) were considered as the basis of Biophilia NLS-research results analysis.
Thus we used a complex of the Biophilia NLS-signs including presence of pathologically changed vessels and change of intestinal wall structure (Table 2).

Biophilia NLS-angiography

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As our researches have shown, for Crohn’s disease following Biophilia NLS-signs are typical.
1. Damage of an intestine wall. It is necessary to notice that wall damage happened in all layers (97.2%), which evidences transmural affection. However in 2.8% of cases changes were detected in mucous-submucous layer. At acute inflammatory process we detected affected lymph nodes of average chromogeneity (4-5 points on Fleindler’s scale) in paraintestinal fiber.
2. Ulcerous defects. Ulcerous defects were characterised by absence of an accurate differentiation of layers in 77.7% of cases, hyperchromogenic inclusions in submucous layer – in 32.3%, total affection of a mucous layer – in 14.4%. Wide and narrow defects of submucous layer with longitudinal orientation were revealed in 31.1% of cases only.
On the basis of the comparative analysis of Biophilia NLS-graphy results and pathomorphological researches we have developed a method of Biophilia NLS-diagnostics of intestines ulcerous affections. At inflammatory process in an intestine, both at Crohn’s disease, and at ulcerative colitis, we marked changes of intestinal wall structure and its chromogeneity. These researches were carried out in a small number of patients with Crohn’s disease. Kuznetsova T.G. et al. has described changes of intestinal wall structure in the form of affected hollow organ symptom, on the basis of which it is possible to carry out differential diagnostics of intestines diseases. We have also revealed other changes in an intestine wall, such as hyperchromogenic inclusions, total affection of a mucous layer, narrow and wide defects of submucous layer, and have proven that such signs are typical for ulcerous affection.
3. Presence of pathologically changed vessels. Biophilia NLS-angiography have shown expressed changes of intestine wall vessels in 52.6% of cases, in 17.9% – average expressiveness of changes, in 11.6% – minor changes, in 17.9% of patients affection of vessels was not identified. Severe changes of a vascular wall evidence activity of inflammatory process. We have also investigated quantitative characteristics of a bloodflow in an intestine wall at inflammatory process, such as an index of resistance and speed of a bloodflow, which were compared to the results of central haemodynamics. We have found mechanisms of bloodflow abnormalities in an intestine wall, depending on expressiveness of inflammatory process according to Biophilia NLS-graphy.

4. Presence infiltration, fistulas, strictures and perianal complications, diagnostics of which will not be given in this article.