
Efficiency of one of the most widely spread
rheumatic disease – rheumatoid arthritis (RA) treatment has increased greatly in
the last decade because of development and introduction into clinical practice
of new medications, which can prevent inevitable progressing of joints
destruction and joint dysfunction in patients with RA. Studies of RA
pathogenesis allowed to make a conclusion about necessity in active early
treatment, application of basic anti-inflammatory therapy (BAIT), because it can
help to modify clinical course of the disease more efficiently and also it
ensures positive prognosis for functional condition of affected joints.
Appearance of new group of preparations – biological agents (antycytoktine
therapy) and their application in combination with traditional means of BAIT
allow to achieve a significant success in treatment of RA patients. At the same
time it was found that duration of “therapeutic period” – a period of time since
the moment of definite RA diagnosing till the moment when active therapy poorly
affects joints destruction – is quite short – a year approximately, and the best
results are achieved in the beginning of a therapy, within first three months
since the incursion of the disease.
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